Free shipping over $60·60-day happiness guarantee·Plastic-free packaging
For
Dogs & cats
Form
Soft chew
Supply
60 chews

Calm & sleep

Tryptophan Calm Chews

4.6 · 129 reviews
$29

The serotonin route: tryptophan plus a B6 cofactor.

Size
Purchase
1
Free shipping over $60 · 60-day returns
60-day returns, even if the tub is open
Batch certificate of analysis on request
Ingredients & amounts
Per serving as stated
L-tryptophan250 mg
Pharmaceutical grade
Vitamin B62 mg
Pyridoxal-5-phosphate
Magnesium50 mg
Magnesium glycinate
GABA100 mg
Gamma-aminobutyric acid
Guaranteed analysis
Crude proteinmin 13%
Crude fatmin 7%
Crude fibremax 4%
Moisturemax 15%
Feeding guide
Cats½ chew daily
Up to 10 kg1 chew daily
10–25 kg2 chews daily
Over 25 kg3 chews daily

Give on an empty stomach if possible, 45 minutes before the stressful event, for best absorption.

Sourcing & quality

Produced to our specification in an FDA-registered, cGMP facility and released against a batch certificate of analysis covering identity, potency, heavy metals and microbials. Supplier qualification file, including facility registration and third-party test reports, is available on request.

Shipping & returns

Ships in 1–3 business days. Free over $60. Sixty-day returns on opened tubs — see returns & refunds and shipping.

The formula

Tryptophan Calm Chews, and why it is built this way

L-tryptophan is the precursor to serotonin, but it only converts if B6 and magnesium are present and if it is taken without competing large neutral amino acids — which is why this formula pairs it with a carbohydrate carrier and B6 rather than selling tryptophan alone.

No 5-HTP — the combination with SSRIs is a genuine risk we avoid.

A dogs & cats at home

What it does

Three things you can expect

01

Supports serotonin production

The pathway behind mood and settle-down behaviour.

02

Cofactors included

B6 and magnesium are required for the conversion step.

03

For cats too

Half a chew for cats, crumbled over wet food.

The detail

Everything on the label, in full

Active ingredients
L-tryptophan250 mg
Pharmaceutical grade
Vitamin B62 mg
Pyridoxal-5-phosphate
Magnesium50 mg
Magnesium glycinate
GABA100 mg
Gamma-aminobutyric acid
Guaranteed analysis
Crude proteinmin 13%
Crude fatmin 7%
Crude fibremax 4%
Moisturemax 15%
Feeding guide
Cats½ chew daily
Up to 10 kg1 chew daily
10–25 kg2 chews daily
Over 25 kg3 chews daily

Give on an empty stomach if possible, 45 minutes before the stressful event, for best absorption.

Sourcing & quality

Made to a specification, released against a test report.

Facility

Manufactured in an FDA-registered facility operating under cGMP for animal nutritional products.

Batch testing

Identity, potency, heavy metals and microbials on every lot. Certificate of analysis available by lot number.

What's not in it

No 5-HTP — the combination with SSRIs is a genuine risk we avoid.

Traceability

Named suppliers for every active. Ask for the sourcing sheet that sits behind this product.

From the household

What owners say

All supplements →
"Fireworks night: he slept through most of it instead of shaking in the bathroom."
Ruth K. — Tryptophan Calm ChewsVerified
"A vet visit without the trembling. That is enough for me."
Lilian G. — Tryptophan Calm ChewsVerified
"Not a sedative — he is still himself, just less on edge at the doorbell."
Ben S. — Tryptophan Calm ChewsVerified

Questions

Before you buy

Can I combine this with the Calming Chews?
Pick one. Both raise serotonergic tone and stacking them is unnecessary.
Is tryptophan safe long term?
At these doses, yes. Very high doses have been linked to eosinophilic myositis in dogs, which is why we cap at 3 chews.
Why does it say 'with food' on the tub but 'empty stomach' here?
A small amount of carbohydrate improves uptake; a full meal introduces competing amino acids. Give it with a biscuit, not dinner.

Goes with

Pairs well with

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